2025

Integrate and conquer: pan-cancer proteogenomics uncovers cancer vulnerabilities and therapeutic opportunities

Nature

Debomita Chakraborty, Rossana Romero, Krishnaraj Rajalingam 

10.1038/s41392-024-02009-6

TP05

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CETSA-MS unveils novel targets engaged by rigosertib to promote anit-tumor activity and inflammatory responses

iScience

Petros Kechagioglou, Hajime Yurugi, Camille Dupont, Alexey Chernobrovkin, Rossana Romero, Gregory Harms, Marie Oster, Sandra Ciesek, Rebecca Tweedell, Thirumaladevi Kanneganti, Stefanie Zimmer, Stephen Cosenza, Steven M. Fruchtman, Krishnaraj Rajalingam

10.1016/j.isci.2025.112748

TP05

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Assessing customized mulitvalent chemokine – binding peptide treatment in a murine m odel of coxsackievirus B3 myocarditis

Basic Res Cardiol

Kelm N, Kespohl M, Smagurauskaite G, Vales S, Karuppanan K, Mburu P, Thiele A, Pinkert S, Bukur T, Mülleder M, Berndt N, Klingel K, Gaida MM, Bhattacharya S, Beling A

10.1007/s00395-025-01098-w

TP22, TP02

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ACC1 is a dual metabolic-epigenetic regulator of Treg stability and immune tolerance

Mol Metab.

Stüve P, Godoy GJ, Ferreyra FN, Hellriegel F, Boukhallouk F, Kao YS, More TH, Matthies AM, Akimova T, Abraham WR, Kaever V, Schmitz I, Hiller K, Lochner M, Salomon BL, Beier UH, Rehli M, Sparwasser T, Berod L

10.1016/j.molmet.2025.102111

TP18

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Role of CYLD in brain physiology and pathology

J Mol Med (Berl.)

Nardi L, Bicker F, Maier J, Waisman A, Schmeisser MJ

10.1007/s00109-025-02521-4

TP15

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Targeting the Menin-KMT2A interaction in leukemia: Lessons learned and future directions

Int J Cancer

Perner F, Gadrey JY, Armstrong SA, Kühn MWM

10.1002/ijc.35332

IRTG